Posts Tagged ‘Morphine’

Album reviews: Cure For Pain, by Morphine

January 28th, 2010

I got ‘Cure For Pain’ as soon as it came out and it still finds its way to my cd player. Every time I listen to this album I get the feeling of a dark, smoky, almost underground Boston atmosphere, full of Sandman’s distinctive, deep vocals, anchored by two string slide bass, baritone sax and a drum kit. Morphine intertwines a sound that cannot be easily categorized as rock or blues. Instead, they call to mind lounge jazz elements mingled with the grind of blues, inviting me gradually into a dark alcove of sound, while maintaining rock & roll provisions.

‘Cure For Pain’ is a fearless, energetic album with blasting saxophone-riffs and resounding bass. Morphine’s sounds are smooth, with bluesy sax tunes flirting around deep basslines. Sandman’s songwriting is deceivingly simple, yet craftily performed, his voice a lyrical sensibility, a gloomy mournful bass that echoes despair, confusion, and melancholy. Colley’s sax is at times raw, at times refined; Conway’s drums drive the music alongside Sandman’s groovy basslines. What makes the album a classic is that, although the Boston trio doesn’t uncover much versatility in its instruments, still it produces an unremitting depth on its sound, nothing like the agreeable state of unconsciousness associated with their namesake drug.

It’s pretty much impossible for an album to have nothing but great songs on it. ‘Cure For Pain’, however, is full of great tracks that switch from sad to blues and upbeat jazz, always reflecting an extraordinary chemistry between Sandman, Conway and Colley. Mixing jazz elements with grunge sounds, admittedly, the album’s highlights are the title track ‘Cure For Pain’, ‘Buena’, ‘Candy’ and ‘Thursday’. Yet, the album has other great tracks such as ‘Dawna’, the haunting opening of the album; ‘In Spite of Me’ with Sandman’s whispering voice drifting over reverb drenched mandolins; ‘Miles Davis Funeral’, the atmospheric album’s finale.

Mark Sandman is deeply missed. And Morphine that disbanded immediately after Sandman’s untimely death from heart attack, are deeply missed too from the low rock scene for their jazz and blues conventions that sculptured their own world of gloomy rock beauty. However, the genius of the Boston trio is not lost. It still remains on their moodiness that drips out of ‘Cure For Pain’ mostly from Sandman’s slow-burning passion for the women he writes and sings about. With his velvet, deep voice makes cold, rainy nights fearful, but also savoury. This is the genius of Morphine.

‘Cure for Pain’ is, without any doubt, one of the best and most progressive rock albums of the ’90s.



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What you Have to Know About Opiate Addiction

January 28th, 2010

Drug addiction is an enormous worldwide catastrophe. Opium-based drugs became some of the most common addictive drugs nowadays. Opium-derived drugs are widely accessible and tremendously circulated all over the world. Before discussing opium-based addiction, its nature, and its treatment procedures, it is necessary to learn more about the opium-derived substance first.

Basically, an opiate is a substance that is derived from the sleep-bringing poppy plant. The major variants of opium-derived compounds include codeine, papaverine, heroin, morphine, and thebaine. Amusingly, two of the most popular kinds of opium-derived compounds, morphine and heroine, have identical chemical structures. Due to this feature, heroin can be discovered through urine screening when morphine is being administered to the body. According to medical science, heroin has the potential to be a central nervous system tranquilizer and it has the capability to enter the brain faster when compared to morphine. As a matter of fact, both substances are even used as analgesics and narcotics that provide relaxing effects.

(1) Morphine: Morphine or opiate analgesic drug is the most popular and the most obtainable opium-derived compound in the world today. Morphine is a variant of alkaloid. Morphine is very essential in the field of medicine since it is utilized in the treatment of disorders such as the swelling of the lungs. An oversupply of morphine can produce plenty of troubles to the physical condition of the drug dependent person. The health complications triggered by an oversupply morphine include respiratory depression, pulmonary edema, congestive cardiac failure, respiratory system failure, coma, as well as death.

(2) Codeine: Codeine is slightly similar to morphine, content-wise. Codeine is also considered to be a medication for treating cough, severe and acute pain, bowel syndrome, and diarrhea. Codeine overdose can create several complications such as itching, nausea, euphoria, miosis, dry mouth, vomiting, urinary retention, constipation, hypotension, respiratory complications, and drowsiness.

(3) Papaverine and Thebaine: The structural make-up of thebaine is slightly akin to those of morphine and codeine. Thebaine also goes by the name of paramorphine. This sort of drug is not used alone. Some of the substances that are used with thebaine include naltrexone, naloxone, oxymorphone, oxycodone, nalbuphine, etorphine, and buprenorphine. An oversupply of thebaine is absolutely similar to the side-effects of morphine and codeine.

(4) Heroin: Heroin is referred to as a semi-synthetic sedative. Because the demand for this opiate is very high, heroin enterprise is also one of the fastest growing illegal industries. The most popular means of abusing heroin is the utilization of the substance to the body by means of an injection. Heroin is also known by the trademark name Diamorphine. Dependence to heroin may result to AIDS and other sexually-transmitted diseases. An oversupply of heroin may initiate acute difficulties like chronic constipation, renal failure, respiratory depression, profound unconsciousness, as well as death.

The lone source of opium-based compounds is the poppy plant. The quality of opium-based compounds is dependent on the moisture content of the poppy plant.

The liquid form of opium-based compounds is called methadone, a substance that is utilized in the removal of toxins from the body of drug dependent people. An oversupply of methadone may cause addiction.

Opium-based drugs have a few beneficial side-effects on the body in situations where they are prescribed by medical experts as pain relievers. When overdosed, opium-based compounds may initiate a few severe troubles. Addiction to opiates may progress to physical and psychiatric dependence. Muscle spasm is a common side-effect that resulted from the constant use of opium-based compounds. Respiratory complications are considered to be some of the side-effects of opiate drugs. The other side-effects of opium-based addiction include cracked lips, skin rashes, hypotension, and constipation. Addiction to opium-derived compounds may damage the central nervous system and it may initiate lethargy and coma. Eventually, a continuous usage of opium-based compounds can cause the death of the person who has drug addiction problems.

The treatment procedures for opium-based addiction may be performed in a residential or a non-residential basis. The full treatment method in both cases is classified into two components: the detox and the advising. Detox includes the riddance of toxic substances from addictive patient’s body. In advising, the drug dependent person is motivated to live a better life.

While the patient is experiencing the different treatment procedures, support from his relatives, his loved ones, and the society are extremely necessary.



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Hydrocodone: Prescription Drug Abuse & Testing

January 17th, 2010

Hydrocodone or dihydrocodeinone is a semi-synthetic opioid derived from two of the naturally occurring opiates, codeine and thebaine.

Hydrocodone Prescription, Dosage & Administration:

Hydrocodone is an orally active, narcotic analgesic and antitussive. Being a narcotic analgesic, it is prescribed for the relief of moderate to severe pain & being a antitussive, it is prescribed as a medicine used to suppress or relieve coughing.

Hydrocodone comes both as a tablet and also in liquid form & thus can easily be taken orally. 5 mg of hydrocodone is equivalent to 30 mg of codeine when administered orally. Earlier hydrocodone and morphine were considered equipotent for pain control in humans. However, it is now considered that a dose of 15 mg of hydrocodone is equivalent to 10 mg of morphine. Hydrocodone is considered to be morphine-like in all respects and thus, final dosage is adjusted by physician according to the severity of the pain and the response of the patient.

Hydrocodone Abuse:

Vicodin i.e. hydrocodone in combination with acetaminophen, is a commonly abused version of hydrocodone in United States and Canada. Vicodin, as with all narcotic analgesics, can be habit forming—causing dependence, tolerance, and withdrawal symptoms if not used as it is prescribed. The presence of acetaminophen in hydrocodone-containing products deters many drug users from taking excessive amounts.

Effects of Hydrocodone Abuse:

Some of the common side effects of drug abuse include dizziness, lightheadedness, nausea, drowsiness, euphoria, vomiting, and constipation. Some of the lesser common side effects are various allergic reactions, blood disorders, mood swings, mental fogginess, anxiety, lethargy, difficulty in urinating, ureter spasms, rashes and irregular or depressed respiration etc.

Physical Dependence on Hydrocodone:

Opioid analgesics such as Hydrocodone may cause psychological and physical dependence. Physical dependence results in withdrawal symptoms in patients who abruptly discontinue the drug. Physical dependence usually does not occur to a clinically significant degree until after several weeks of continued opioid usage, but it may occur after as little as a week of opioid use.

Commercial Status in United States:

There are over 200 products containing hydrocodone in the U.S. When sold commercially in the US, hydrocodone is always combined with another medication due to a separate federal regulation. In its most usual forms, hydrocodone is combined with acetaminophen. Such commercial hydrocodone products which are combined with acetaminophen are known by various trademark names such as Vicodin & Lortab. Hydrocodone also can be combined with aspirin (Trade name: Lortab ASA), ibuprofen (Trade name: Vicoprofen), & certain antihistamines (Trade name: Hycomine).

Pure Hydrocodone tablets or capsules are not offered currently by any USA drug company. The cough preparation Codiclear DH is the purest available US hydrocodone item, containing guaifenesin and small amounts of ethanol as active ingredients.

With such a huge number of Hydrocodone containing products, the possibility of misuse and addiction remains substantial. As a result, Sales and production of this drug has increased significantly in recent years & so has its diversion and illicit use. To limit abuse of opioid drugs like Dilaudid it is necessary to properly assess the patient, employ proper prescription practices, periodically re-evaluate the opioid therapy, and properly dispense and store the drugs.

Hydrocodone Testing:

Hydrocodone may not cause a positive result in a standard opiate urine test. Many opiate tests test only for morphine (which both codeine and heroin break down into). This is true for both home/business kits and laboratory testing.

However, there are several specialized home and laboratory testing kits available that specifically detects hydrocodone (& hydromorphone, its metabolic product). So test results usually depend on the particular type of test that is used and whether or not laboratory verification is done. If a home drug test is given and the opiate test shows a positive result (due to hydromorphone use), laboratory verification might not result in a positive test because the lab may only test for morphine.



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