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How long do tramadol withdrawal symptoms last?

June 14th, 2010
m123 asked:


I stopped using tramadol cold turkey (after heavy use for about a month) about 3 and a half weeks ago and I have no more actual “withdrawals” but I still feel severly depressed. I was not nearly this depressed before I started using tramadol. The week after I stopped I had thoughts of suicide, the depression was so bad. So how much longer is this depression supposed to last?

Anyone have any insight on this?

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What is Tramadol

January 26th, 2010

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Generic Name: tramadol (TRAM a dol)

Brand Names: Ultram, Ultram ER

What is tramadol?

Tramadol is a narcotic-like pain reliever.

Tramadol is used to treat moderate to severe pain. Tramadol extended-release is used to treat moderate to severe chronic pain when treatment is needed around the clock.

Tramadol may also be used for other purposes not listed in this medication guide.

Important information about tramadol

You should not take tramadol if you have ever been addicted to drugs or alcohol.

Seizures (convulsions) have occurred in some people taking tramadol. You may be more likely to have a seizure while taking tramadol if you have a history of seizures or head injury, a metabolic disorder, or if you are taking certain medicines such as antidepressants, muscle relaxers, or medicine for nausea and vomiting.

Take tramadol exactly as it was prescribed for you. Do not take it in larger doses or for longer than recommended by your doctor. Do not take more than 300 milligrams of tramadol in one day.

Seek emergency medical attention if you think you have used too much of this medicine. A tramadol overdose can be fatal. Overdose symptoms of a tramadol overdose may include drowsiness, shallow breathing, slow heartbeat, extreme weakness, cold or clammy skin, feeling light-headed, fainting, or coma. Tramadol may be habit-forming and should be used only by the person it was prescribed for. Tramadol should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Tramadol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Do not stop using tramadol suddenly, or you could have unpleasant withdrawal symptoms such as anxiety, sweating, nausea, diarrhea, tremors, chills, hallucinations, trouble sleeping, or breathing problems. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Do not crush the tramadol tablet. This medicine is for oral (by mouth) use only. Powder from a crushed tablet should not be inhaled or diluted with liquid and injected into the body. Using this medicine by inhalation or injection can cause life-threatening side effects, overdose, or death.

Before taking tramadol

You should not take tramadol if you have ever been addicted to drugs or alcohol, if you are currently intoxicated (drunk), or if you have recently used any of the following drugs:





alcohol;





narcotic pain medicine;





sedatives or tranquilizers (such as Valium);





medicine for depression or anxiety;





medicine for mental illness (such as bipolar disorder, schizophrenia); or





street drugs.





Seizures have occurred in some people taking tramadol. Your risk of a seizure may be higher if you have any of these conditions:





a history of drug or alcohol addiction;





a history of epilepsy or other seizure disorder;





a history of head injury;





a metabolic disorder; or





if you are also taking an antidepressant, muscle relaxer, or medicine for nausea and vomiting.





Talk with your doctor about your individual risk of having a seizure while taking tramadol.

Before taking tramadol, tell your doctor if you are allergic to any drugs, or if you have:





kidney disease;





liver disease;





a stomach disorder; or





a history of depression, mental illness, or suicide attempt.





If you have any of these conditions, you may need a dose adjustment or special tests to safely take tramadol.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tramadol may also cause serious or fatal side effects in a newborn if the mother uses the medication during pregnancy or labor. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Tramadol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Tramadol should not be given to a child younger than 18 years of age.

www.whytramadol.blogspot.com



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Darvocet, Darvon & Tylenol: Prescription Drug Abuse & Testing

January 22nd, 2010

Dextropropoxyphenes:

These are the mild analgesic agents of the opioid category which are frequently used to treat mild to moderate pain. These are also used as antitussive i.e. a medicine used to suppress or relieve coughing.

Use & Abuse:

Dextropropoxyphene, like codeine, is a weak opioid. However, approximately 10-20% of the Caucasian population is unable to metabolize codeine, so dextropropoxyphene is particularly useful with such people. In pure form, dextropropoxyphene is commonly used to ease the withdrawal symptoms in people addicted to opioids. Being very weak in comparison to the opioids that are commonly abused, dextropropoxyphene can only act as a “partial” substitute. It does not have much effect on mental cravings; however it can be effective in alleviating physical withdrawal effects, such as muscle cramps.

Dextropropoxyphene has been a subject to some controversy. While many physicians prescribe it for a wide range of mildly to moderately painful symptoms as well as for treatment of diarrhea, many others refuse to prescribe it, citing its highly addictive nature and limited effectiveness.

Tylenol:

It is a popular American brand of drugs for relieving pain, reducing fever, and relieving the symptoms of allergies, cold, cough, and the flu. The active ingredient of its original, flagship product, acetaminophen (called “paracetamol” outside North America), is marketed for headaches, fever, muscle and body pain, arthritis, and joint pain. Like the words “acetaminophen” and “paracetamol”, the brand name is derived from the chemical name for the compound, N-acetyl-para-aminophenol (APAP). It is available over the counter without prescription, has few side effects, and reacts with very few medications. Acetaminophen is also found in other narcotic based analgesics such as Percocet which contains oxycodone. However, some classes of stronger pain relievers also contain codeine.



Darvon:

Darvon is a pure dextropropoxyphene preparation available in the U.S. that does not contain acetaminophen (Tylenol). It was made by Eli Lilly. It came under heavy fire in 1978 by consumer groups which said that Darvon was associated with suicide. Darvon was never withdrawn from the market, but Lilly has waged a sweeping, and largely successful, campaign among doctors, pharmacists and Darvon users to defend the drug as safe when it is used in proper doses and not mixed with alcohol.

Darvocet:

In the United States, dextropropoxyphene hydrochloric acid is available as a prescription formulation with acetaminophen (Tylenol) in ratio anywhere from 30mg / 600mg to 100mg / 650mg, respectively. These are usually named as Darvocet.

Dextropropoxyphene/Acetaminophen Testing:

A diverse array of techniques is available to test for drug abuse and Dextropropoxyphenes and/or acetaminophen containing compounds are no exception. As shown in the figure below, some amount of acetaminophen remains unchanged while rest of it forms different metabolites. Same is true for Dextropropoxyphenes and derivative compounds like Darvon.

Tylenols & Darvocets can be detected by acetaminophen specific methods while Darvons can be detected by Dextropropoxyphene specific methods, be it urine or hair drug testing based, GC/MS based diagnostic techniques or Antibody based kits.

These unchanged Dextropropoxyphenes & acetaminophen compounds and their metabolized products can be detected using any of the following methods:

•Urine based Dextropropoxyphene/acetaminophen/metabolite testing

•Hair follicle based Dextropropoxyphene/acetaminophen/metabolite detection

•GC based Dextropropoxyphene/acetaminophen/metabolite detection

•Mass spec based Dextropropoxyphene/acetaminophen/metabolite testing

•Dextropropoxyphene / acetaminophen / metabolite-specific antibody based diagnostic kits



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